An interesting case study of St. Louis if a bit long. This repeats the pattern seen everywhere in the US, certainly, and other places also. The collapse of the US federal government produced a lack of coordination and will result in thousands of more deaths.
I see this as an immediate shock in a much larger collapse of nation-states as a primary political entity. But at the practical level, despite the confusion action is being taken at the metropolitan and state level. This a rapid evolution of authority in the face of a complete power vacuum.
That doesn’t answer the question of coordination as that is the significant failure of the idea of completely sovereign regions with no planetary standard. What we have has no power and so it unable to do more than suggest aid or provide some emergency stop-gap services.
I am also concerned with how to end this. In terms of the publicly available epidemiology, this will not be over until sometime this summer or maybe next year. You are absolutely correct that there is no one who will be able to say it is over. I expect this will fall on whoever wins the presidential election this fall. But no one will be believed as they are all without any credibility. Another present from the Trump Party.
Historically this is the kind of thing (no real example) that leads to conquest or failing into warlordism, i.e. feudalism.